Structure of PDB 8ypk Chain C

Receptor sequence
>8ypkC (length=199) Species: 10090 (Mus musculus) [Search protein sequence]
TTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAAD
CSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMI
CGWDKRGPGLYYVDSEGNRISGTAFSVGSGSVYAYGVMDRGYSYDLKVEE
AYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHDKYS
3D structure
PDB8ypk Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor.
ChainC
Resolution2.7 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1L0C C T2 A20 T21 K33 A46 G47 A49 G129 S130 T1 A19 T20 K32 A45 G46 A48 G128 S129
External links
PDB RCSB:8ypk, PDBe:8ypk, PDBj:8ypk
PDBsum8ypk
PubMed38906067
UniProtO55234|PSB5_MOUSE Proteasome subunit beta type-5 (Gene Name=Psmb5)

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