Structure of PDB 8xtg Chain C

Receptor sequence
>8xtgC (length=393) Species: 5074 (Penicillium brevicompactum) [Search protein sequence]
PASIIQELASAAKQYENNESGAREALIAQSRALIASLEVPSEFIQHTFWS
QPALSAIVRLATDVNLFQYLKDAQEEGLNAEALASKTGMDVSLFARLARH
LVAMNVITSRNGVFYGTALSNGLAAENYQQSIRFCHDVSRPSFGAFPSFF
KGNGYKTPALGTTDGPFQSAHKVDISFPQWLVGNPPYLQYFNSYMSAYRA
GKPNWCDNGFYPVADRLLNGFDASVSDVLLVDVGGGRGHDIATFGSQFSP
LPGRLVLQDREQVINSIPADESRQFEATTHDIFTTQPVKHARAYYMHSVP
HGFGDEDAVKIMANLVPALAKGYSRVLLNEIVVDEERPVMSATNMDLIML
AHMGAKERTEADWRSILTRAGLKVVNIYSYPGVAESLIEAELA
3D structure
PDB8xtg Structural basis for substrate flexibility of the O-methyltransferase MpaG' involved in mycophenolic acid biosynthesis.
ChainC
Resolution2.0 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH C M200 Y203 G239 H244 D264 R265 H285 D286 I287 H302 S303 M195 Y198 G234 H239 D259 R260 H280 D281 I282 H297 S298
BS02 A1LWD C Y199 M200 Y203 R265 S303 H306 I353 M354 Y194 M195 Y198 R260 S298 H301 I348 M349
External links
PDB RCSB:8xtg, PDBe:8xtg, PDBj:8xtg
PDBsum8xtg
PubMed39150221
UniProtA0A0B5L781|MPAG2_PENBR O-methyltransferase mpaG' (Gene Name=mpaG')

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