Structure of PDB 8x7u Chain C

Receptor sequence
>8x7uC (length=654) Species: 311400 (Thermococcus kodakarensis) [Search protein sequence]
MDREEMIARFAKFLINRLKDLLTVTPKRSLAIDWAHLNSFDPELADELLN
NPEEAIASAEDAIQIVLREPPLLVEREFKVHARFYNLPKTLLVKELGSEH
INKLIQVEGIITRVSEVKPFVEKAVFVCRDCGNEMVRLQRPYENLVKPAK
CDACGSRNIELDVDKSRFLNFQSFRLQDRPESLKGGQMPRFVDAILLDDL
VDAALPGDRVLVTGVLRVILEQREKRPIFKKILEVNHIEQLSKEIEELEI
SPEDEQKIRELAKRKDIVDAIVDSIAPAIWGHRIVKKGIALALFGGVQRT
LPDGTKLRGESHVLLVGDPGVAKSQLLRYVANLAPRAIYTSGKSSSAAGL
TAAAVRDEFTGSWVLEAGVLVLADGGFALIDEFDKMSDRDRSAIHEALEQ
QTISISKAGITATLNSRTTVIAAANPKFGRFNRHKSLPEQLDLPPTLLSR
FDLIFLLLDEPDEKVDASIAEHILKVRRGEAEAVTPKIPYDLLKKYIAYA
RKNVHPVLSREAMEEIKRYYVKMRKGLRRGDEDGVQPIPITARQLEALIR
LSEAHARMRLSETVTREDARAAIEIIEAMMKTIAVDEEGNLDVSILEVGK
SSKKINKIEKPEEKVIEAAKQAGIGTKADIEKLLNELKSDGRVYEPRAGF
YRVI
3D structure
PDB8x7u MCM in complex with dsDNA in presence of ATP
ChainC
Resolution3.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C A290 I291 W292 P331 G332 V333 A334 K335 S336 Q337 I481 A278 I279 W280 P319 G320 V321 A322 K323 S324 Q325 I469
BS02 ATP C A554 R555 E558 A542 R543 E546
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0032508 DNA duplex unwinding

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Molecular Function
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Biological Process
External links
PDB RCSB:8x7u, PDBe:8x7u, PDBj:8x7u
PDBsum8x7u
PubMed
UniProtQ5JIT1

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