Structure of PDB 8wpp Chain C

Receptor sequence
>8wppC (length=218) Species: 10244 (Monkeypox virus) [Search protein sequence]
MNSVTISHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFF
IQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLT
GVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHITK
HVSVLYCLGKTDFSNIRAKLESPVTTIVGYHPAARDHQFEKDRSFEIINV
LLELDNKTPINWAQGFIY
3D structure
PDB8wpp Structural insights into the assembly and mechanism of monkeypox virus DNA polymerase complex F8-A22-E4-H5
ChainC
Resolution3.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.2.2.27: uracil-DNA glycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C K160 T161 Y180 H181 A184 R185 K160 T161 Y180 H181 A184 R185
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0016787 hydrolase activity
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
Biological Process
GO:0006281 DNA repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8wpp, PDBe:8wpp, PDBj:8wpp
PDBsum8wpp
PubMed37995690
UniProtM1LL92|UNG_MONPV Uracil-DNA glycosylase (Gene Name=OPG116)

[Back to BioLiP]