Structure of PDB 8w8g Chain C

Receptor sequence
>8w8gC (length=208) Species: 9606 (Homo sapiens) [Search protein sequence]
EDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHG
LSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSI
EKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFERIFGDPNSHMPFK
SKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAA
KVVESKRT
3D structure
PDB8w8g PinX1 suppress tumorigenesis through inhibiting telomerase activity
ChainC
Resolution2.7 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C E238 S242 N245 E177 S181 N184
BS02 peptide C R102 N103 E106 I109 H110 L120 I123 Q127 T130 R131 L138 D139 A140 Q141 F142 E146 R147 E192 R41 N42 E45 I48 H49 L59 I62 Q66 T69 R70 L77 D78 A79 Q80 F81 E85 R86 E131
External links
PDB RCSB:8w8g, PDBe:8w8g, PDBj:8w8g
PDBsum8w8g
PubMed
UniProtP54274|TERF1_HUMAN Telomeric repeat-binding factor 1 (Gene Name=TERF1)

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