Structure of PDB 8w1p Chain C

Receptor sequence

>8w1pC (length=324) Species: 2053611 (Selenomonas sp.) [Search protein sequence]

VTLKSRPENLSFARCLNTTEAKFWQTDFLKRHTFKLPLLITDKAVLASKG
HEMPPDKLEKEIMDPNPQKSQSCTLSTECDTLRIDFGIKVLPVKESMYSC
SDYNYRTAIYQKIDEYIAEDGFLTLAKRYVNNIANARFLWRNRKGAEIIE
TIVTIEDKEYPSFNSKSFNLDTFVEDNATINEIAQQIADTFAGKREYLNI
YVTCFVKIGCAMEVYPSQEMTFDDDDKGKKLFKFEGSAGMHSQKINNALR
TIDTWYPDYTTYEFPIPVENYGAARSIGIPFRPDTKSFYKLIDRMILKNE
DLPIEDKHYVMAILIRGGMFSKKQ

3D structure

PDB

8w1p Structural determinants of precise DNA cleavage by a CRISPR HNH-Cascade system

Chain

Resolution

3.5 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	C	S20 F21 A22 R23 V54 L55 A56 Y107 R150 Q227 M229 H250 K253 N256 R259 R284 G326 G327 M328	S11 F12 A13 R14 V45 L46 A47 Y98 R141 Q218 M220 H241 K244 N247 R250 R275 G317 G318 M319
BS02	dna	C	E17 K58 H60 D73 P74 N75 P76 Q77 F231 M328 K331 K332	E8 K49 H51 D64 P65 N66 P67 Q68 F222 M319 K322 K323

External links

PDB	RCSB:8w1p, PDBe:8w1p, PDBj:8w1p
PDBsum	8w1p
PubMed	39111310

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