Structure of PDB 8w0a Chain C

Receptor sequence
>8w0aC (length=636) Species: 9606 (Homo sapiens) [Search protein sequence]
KLLLANWGLPKAVLEKYHSFGVKKMFEWQAECLLLGQVLEGKNLVYSAPT
SAGKTLVAELLILKRVLEMRKKALFILPFVSVAKEKKYYLQSLFQEVGIK
VDGYMGSTSPSRHFSSLDIAVCTIERANGLINRLIEENKMDLLGMVVVDE
LHMLGDSHRGYLLELLLTKICYITRKSNAVQIVGMSATLPNLELVASWLN
AELYHTDFRPVPLLESVKVGNSIYDSSMKLVREDHVVSLCYETICDNHSV
LLFCPSKKWCEKLADIIAREFYNLHEQKELLEVMDQLRRLPSGLDSVLQK
TVPWGVAFHHAGLTFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRV
IIRTPIFGGRPLDILTYKQMVGRAGRKGVDTVGESILICKNSEKSKGIAL
LQGSLKPVRSCLVTGSMIRAILEIIVGGVASTSQDMHTYAACTFLAASMG
AIEACVMWLLENEFIQVYHPTHLGSATLSSSLSPADTLDIFADLQRAMKG
FVLENDLHILYLVTPMFEDWTTIDWYRFFCLWEKLPTSMKRVAELVGVEE
GFLARCQHRQMAIHKRFFTSLVLLDLISEVPLREINQKYGCNRGQIQSLQ
QSAAVYAGMITVFSNRLGWHNMELLLSQFQKRLTFG
3D structure
PDB8w0a Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
ChainC
Resolution3.2 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C F146 V147 G173 T190 E192 R193 R200 K347 A418 S444 S622 E659 V757 G760 M761 V764 F79 V80 G106 T123 E125 R126 R133 K257 A311 S337 S481 E518 V605 G608 M609 V612
External links
PDB RCSB:8w0a, PDBe:8w0a, PDBj:8w0a
PDBsum8w0a
PubMed38895274
UniProtO75417|DPOLQ_HUMAN DNA polymerase theta (Gene Name=POLQ)

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