Structure of PDB 8vqy Chain C

Receptor sequence
>8vqyC (length=334) Species: 9606 (Homo sapiens) [Search protein sequence]
SNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMD
YTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFV
HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES
YGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYP
RLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGIT
TVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIF
FSQPARAAAIDRWSRIFFPVVFSFFNIVYWLYYV
3D structure
PDB8vqy Structural insights into GABA A receptor potentiation by Quaalude.
ChainC
Resolution2.82 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ABU C E155 Y157 F200 T202 Y205 E149 Y151 F194 T196 Y199
BS02 A1ADG C T262 N265 F289 T256 N259 F283
BS03 Q3G C W241 I322 W235 I316
External links
PDB RCSB:8vqy, PDBe:8vqy, PDBj:8vqy
PDBsum8vqy
PubMed38898000
UniProtP47870|GBRB2_HUMAN Gamma-aminobutyric acid receptor subunit beta-2 (Gene Name=GABRB2)

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