Structure of PDB 8val Chain C

Receptor sequence
>8valC (length=373) Species: 562 (Escherichia coli) [Search protein sequence]
GPHMSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTR
GVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAAS
RTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPP
EHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIA
HEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDD
QALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQL
SPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRM
GVEMTLLRALAFHPRMPLPEPEV
3D structure
PDB8val Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
ChainC
Resolution3.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C T99 K100 V101 R105 S132 H134 T102 K103 V104 R108 S135 H137
BS02 ZN C C64 C76 C67 C79
BS03 ADP C A7 W10 R11 P12 V19 G48 V49 G50 K51 T52 S53 L214 R215 A10 W13 R14 P15 V22 G51 V52 G53 K54 T55 S56 L217 R218
BS04 BEF C K51 R215 K54 R218
BS05 MG C T52 D126 T55 D129
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0009360 DNA polymerase III complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8val, PDBe:8val, PDBj:8val
PDBsum8val
PubMed38490435
UniProtP06710|DPO3X_ECOLI DNA polymerase III subunit tau (Gene Name=dnaX)

[Back to BioLiP]