Structure of PDB 8v4p Chain C

Receptor sequence
>8v4pC (length=523) Species: 5476 (Candida albicans) [Search protein sequence]
THNVVHEANGVKLRETPKEFFERQPNKGHIHDVNQYKQMYEQSIKDPQGF
FGPLAKELLSWDHDFHTVKSGTLKNGDAAWFLGGELNASYNCVDRHAFAN
PDKPALICEADDEKDSHILTYGDLLREVSKVAGVLQSWGIKKGDTVAVYL
PMNAQAIIAMLAIARLGAAHSVIFAGFSAGSIKDRVNDASCKALITCDEG
KRGGRTTNIKKLCDEALVDCPTVEKVLVYKRTNNPEIHLTEGRDYYWDVE
TAKFPGYLPPVSVNSEDPLFLLYTTPKGVVHSTAGYLLGAALSTKYIFDI
HPEDILFTAGDVGWITGHTYALYGPLLLGVPTIIFEGTPAYPDYGRFWQI
VEKHKATHFYVAPTALRLLRKAGEQEIAKYDLSSLRTLGSVGEPISPDIW
EWYNEFVGKNQCHISDTYWQTESGSHLIAPLAGVVPNKPGSASYPFFGID
AALIDPVTGVEIEGNDAEGVLAIKDHWPSMARTVYKNHTKYMDTYMNPYP
GYYFTGDGAARDHDGYYWIRGRV
3D structure
PDB8v4p Crystal structure of Acetyl-CoA synthetase 2 in complex with Adenosine-5'-allylphosphate from Candida albicans
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.2.1.1: acetate--CoA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WPO C G417 E418 P419 T442 Y443 W444 Q445 T446 D532 I544 R547 G392 E393 P394 T417 Y418 W419 Q420 T421 D507 I519 R522
BS02 WPO C P171 F194 G196 R222 T227 D336 E361 T363 P151 F174 G176 R202 T207 D311 E336 T338
Gene Ontology
Molecular Function
GO:0003987 acetate-CoA ligase activity
GO:0005524 ATP binding
GO:0016208 AMP binding
GO:0016874 ligase activity
Biological Process
GO:0019427 acetyl-CoA biosynthetic process from acetate

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Molecular Function
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Biological Process
External links
PDB RCSB:8v4p, PDBe:8v4p, PDBj:8v4p
PDBsum8v4p
PubMed
UniProtQ8NJN3|ACS2_CANAL Acetyl-coenzyme A synthetase 2 (Gene Name=ACS2)

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