Structure of PDB 8v30 Chain C

Receptor sequence
>8v30C (length=372) Species: 9606 (Homo sapiens) [Search protein sequence]
ETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPCHQGVMVGMGQKDSY
VGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPT
LLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVL
DSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTT
AEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNE
RFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGT
TMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQ
QMWISKPEYDEAGPSIVHRKCF
3D structure
PDB8v30 Molecular Mechanisms of ACTG2 Mutations Linked to Visceral Myopathy
ChainC
Resolution2.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C G197 Y198 S199 G194 Y195 S196
BS02 peptide C E72 I75 P112 E69 I72 P109
BS03 ADP C G13 S14 G15 L16 K18 G156 D157 K213 E214 G302 Y306 G10 S11 G12 L13 K15 G153 D154 K210 E211 G299 Y303
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0010628 positive regulation of gene expression
GO:0090131 mesenchyme migration
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0030027 lamellipodium
GO:0030175 filopodium
GO:0032982 myosin filament
GO:0044297 cell body
GO:0070062 extracellular exosome
GO:0071944 cell periphery
GO:0072562 blood microparticle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8v30, PDBe:8v30, PDBj:8v30
PDBsum8v30
PubMed38820162
UniProtP63267|ACTH_HUMAN Actin, gamma-enteric smooth muscle (Gene Name=ACTG2)

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