Structure of PDB 8uii Chain C

Receptor sequence
>8uiiC (length=324) Species: 9606 (Homo sapiens) [Search protein sequence]
IRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGK
TSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFK
KGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQ
SRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRA
LNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRNI
TELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGT
NEKIQLSSLIAAFQVTRDLIVAEA
3D structure
PDB8uii Cryo-EM map of human clmap-clamp loader ATAD5-RFC-closed PCNA complex
ChainC
Resolution3.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AGS C V23 Y26 R27 L34 P62 G63 T64 G65 K66 T67 S68 M213 R214 V7 Y10 R11 L18 P46 G47 T48 G49 K50 T51 S52 M197 R198
Gene Ontology
Molecular Function
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0017116 single-stranded DNA helicase activity
GO:0019899 enzyme binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0032508 DNA duplex unwinding
GO:1900264 positive regulation of DNA-directed DNA polymerase activity
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005663 DNA replication factor C complex
GO:0031390 Ctf18 RFC-like complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8uii, PDBe:8uii, PDBj:8uii
PDBsum8uii
PubMed38871854
UniProtP40937|RFC5_HUMAN Replication factor C subunit 5 (Gene Name=RFC5)

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