Structure of PDB 8uh7 Chain C

Receptor sequence
>8uh7C (length=320) Species: 10663 (Tequatrovirus) [Search protein sequence]
SMITVNEKEHILEQKYRPSTIDECILPAFDKETFKSITSKGKIPHIILHS
PSPGTGKTTVAKALCHDVNADMMFVNGSDCKIDFVRGPLTNFASAASFDG
RQKVIVIDEFDRSGLAESQRHLRSFMEAYSSNCSIIITANNIDGIIKPLQ
SRCRVITFGQPTDEDKIEMMKQMIRRLTEICKHEGIAIADMKVVAALVKK
NFPDFRKTIGELDSYSSKGVLDAGILSLVTNDRGAIDDVLESLKNKDVKQ
LRALAPKYAADYSWFVGKLAEEIYSRVTPQSIIRMYEIVGENNQYHGIAA
NTELHLAYLFIQLACEMQWK
3D structure
PDB8uh7 Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM
ChainC
Resolution2.628 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C K80 I81 R85 R111 G113 K81 I82 R86 R112 G114
BS02 08T C E12 Y15 R16 I24 P52 G53 T54 G55 K56 T57 T58 E108 N139 F204 R205 E13 Y16 R17 I25 P53 G54 T55 G56 K57 T58 T59 E109 N140 F205 R206
BS03 MG C T57 E108 T58 E109
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0039686 bidirectional double-stranded viral DNA replication
GO:0039693 viral DNA genome replication
Cellular Component
GO:0005663 DNA replication factor C complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8uh7, PDBe:8uh7, PDBj:8uh7
PDBsum8uh7
PubMed38177685
UniProtP04526|LOADL_BPT4 Sliding-clamp-loader large subunit (Gene Name=44)

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