Structure of PDB 8u2z Chain C

Receptor sequence
>8u2zC (length=510) Species: 10116 (Rattus norvegicus) [Search protein sequence]
GQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFPGFYFGELPLSLAA
CTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVT
SMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYILQRE
IHEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSET
PNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFFVYCLYMIIFTAAAYYRP
VEGLPPYKLKNTVGDYFRVTGEILSVSGGVYFFFRGIQYFLQRRPSLKSL
FVDSYSEILFFVQSLFMLVSVVLYFSQRKEYVASMVFSLAMGWTNMLYYT
RGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFSTAVVTLIEDGKYNS
LYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLI
ALMGETVNKIAQELQRAITILDTEKSAFRSGKLLQVGFTPDGKDDYRWCF
RVDEVNWTTW
3D structure
PDB8u2z Structural basis of TRPV1 modulation by endogenous bioactive lipids.
ChainC
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PIO C I661 A665 L669 I432 A436 L440
BS02 CLR C L577 F580 M677 L371 F374 M448
BS03 CLR C T641 V667 Y671 T412 V438 Y442
BS04 PIO C Y511 S512 L515 F543 M547 T550 N551 Y554 I569 Y305 S306 L309 F337 M341 T344 N345 Y348 I363
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8u2z, PDBe:8u2z, PDBj:8u2z
PDBsum8u2z
PubMed38698206
UniProtO35433|TRPV1_RAT Transient receptor potential cation channel subfamily V member 1 (Gene Name=Trpv1)

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