Structure of PDB 8u0v Chain C

Receptor sequence
>8u0vC (length=821) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
GAIQLLKKVILRSTVCKMDFPKDNLFVVYISDGAQLPSQKGYASIVKCSL
RQSKKSDSDNKSVGIPSKKIGVFIKCDSQIPENHIALSSHLWDAFFTHPM
NGAKIKLEFLQMNQANIISGRNATVNIKYFGKDVPTKSGDQYSKLLGGSL
LTNNLILPTEQIIIEIKKGESEQQLCNLNEISNESVQWKVTQMGKEEVKD
IIERHLPKHYHVKETGEVSRTSKDEDDFITVNSIKKEMVNYLTSPIIATP
AIILDGKQGIGKTRLLKELINEVEKDHHIFVKYADCETLHETSNLDKTQK
LIMEWCSFCYWYGPSLIVLDNVEALFGKPQANDGDPSNNGQWDNASKLLN
FFINQVTKIFNKDNKRIRVLFSGKQKTQINPLLFDKHFVSETWSLRAPDK
HARAKLLEYFFSKNQIMKLNRDLQFSDLSLETEGFSPLDLEIFTEKIFYD
LQLERDCDNVVTRELFSKSLSAFTPSALRGVKLTKETNIKWGDIGALANA
KDVLLETLEWPTKYEPIFVNCPLRLRSGILLYGYPGCGKTLLASAVAQQC
GLNFISVKGPEILNKFIGASEQNIRELFERAQSVKPCILFFDEFDSIAPK
RGHDSTGVTDRVVNQLLTQMDGAEGLDGVYILAATSRPDLIDSALLRPGR
LDKSVICNIPTESERLDILQAIVNSKDKDTGQKKFALEKNADLKLIAEKT
AGFSGADLQGLCYNAYLKSVHRWLSAADQSEVVPGNDNIEYFSINEHGRR
EENRLRLKTLLQQDVVHETKTSTSAASELTAVVTINDLLEACQETKPSIS
TSELVKLRGIYDRFQKDRNGE
3D structure
PDB8u0v The N1 domain of the peroxisomal AAA-ATPase Pex6 is required for Pex15 binding and proper assembly with Pex1.
ChainC
Resolution3.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C F433 G464 I465 G466 K467 T468 R469 L611 F615 P642 F228 G259 I260 G261 K262 T263 R264 L406 F410 P437
BS02 ATP C I699 G700 L702 G741 C742 G743 K744 T745 L746 I873 G910 Q914 I494 G495 L497 G536 C537 G538 K539 T540 L541 I668 G705 Q709
BS03 ATP C D826 R852 R855 D621 R647 R650
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0140318 protein transporter activity
Biological Process
GO:0007031 peroxisome organization
GO:0015031 protein transport
GO:0016558 protein import into peroxisome matrix
GO:0016562 protein import into peroxisome matrix, receptor recycling
GO:0043335 protein unfolding
Cellular Component
GO:0005737 cytoplasm
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005829 cytosol
GO:0016020 membrane
GO:1904949 ATPase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8u0v, PDBe:8u0v, PDBj:8u0v
PDBsum8u0v
PubMed38036174
UniProtP24004|PEX1_YEAST Peroxisomal ATPase PEX1 (Gene Name=PEX1)

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