Structure of PDB 8tzr Chain C

Receptor sequence
>8tzrC (length=273) Species: 9606 (Homo sapiens) [Search protein sequence]
EPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDEEKDKGLQ
TSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSL
DQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDE
FTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKDNPEYSPDPS
IYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAE
KQMKDKQDEEQRLKEEEEDKKRK
3D structure
PDB8tzr Structure of human Wnt3a bound to WLS and CALR
ChainC
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMA C C105 C137 W319 C88 C120 W215
BS02 MAN C G107 D135 G90 D118
BS03 MAN C K111 G124 D317 L318 K94 G107 D213 L214
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0051082 unfolded protein binding
Biological Process
GO:0006457 protein folding
Cellular Component
GO:0005783 endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8tzr, PDBe:8tzr, PDBj:8tzr
PDBsum8tzr
PubMed
UniProtP27797|CALR_HUMAN Calreticulin (Gene Name=CALR)

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