Structure of PDB 8tzo Chain C

Receptor sequence
>8tzoC (length=273) Species: 9606 (Homo sapiens) [Search protein sequence]
EPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDEEKDKGLQ
TSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSL
DQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDE
FTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKDNPEYSPDPS
IYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAE
KQMKDKQDEEQRLKEEEEDKKRK
3D structure
PDB8tzo Structure of human Wnt7a bound to WLS and CALR
ChainC
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMA C C105 W319 V321 C88 W215 V217
BS02 MAN C G106 G107 D135 W319 G89 G90 D118 W215
BS03 MAN C F74 Y109 D317 F57 Y92 D213
BS04 GLC C K111 Y128 M131 K94 Y111 M114
BS05 CA C Q26 K62 D63 K64 D328 Q9 K45 D46 K47 D224
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0051082 unfolded protein binding
Biological Process
GO:0006457 protein folding
Cellular Component
GO:0005783 endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8tzo, PDBe:8tzo, PDBj:8tzo
PDBsum8tzo
PubMed37852257
UniProtP27797|CALR_HUMAN Calreticulin (Gene Name=CALR)

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