Structure of PDB 8twf Chain C

Receptor sequence
>8twfC (length=385) Species: 1034943 (Legionella massiliensis) [Search protein sequence]
KNIKILVIGAGIAGPAICYWLRRFGFSPVLIEKYASIRKGGQALDVRGIA
THIAKEMGIYDQICGMRTRIECGRFVDSSGKVLHEEHGEKFGFRQDDEVE
IVRGDLVEILMKTITDIPCYFNQSIISIQQNSDHVTVNFKDGQVEHYDLV
IAADGIHSATRRMVFDKNEYQLIHLGAYLSTFTIPNYLNLRHIDLECEAN
HKLVSINNDNDPEIARAGFMFLSQHILKDIRDEHEQKQFLCDTFRDFGWE
TQNILNRMSESDDFYFDAITQVKMNSWTKGRIALIGDAGYCPSPLSGQGN
NLAFVGAYILAGELKAADGNYMQAFTRYNALLRPFVDANQEFGVWVSKSF
LVEDEVSKEIAEERSNRTLALIKSVSNAITLPQYE
3D structure
PDB8twf Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes.
ChainC
Resolution2.4 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FAD C I10 G11 I14 A15 E34 K35 R40 G42 G43 Q44 R105 A155 D156 Y267 D289 P296 G301 N302 I8 G9 I12 A13 E32 K33 R38 G40 G41 Q42 R103 A153 D154 Y265 D287 P294 G299 N300
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity

View graph for
Molecular Function
External links
PDB RCSB:8twf, PDBe:8twf, PDBj:8twf
PDBsum8twf
PubMed38493211
UniProtA0A078L5T0

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