Structure of PDB 8th5 Chain C

Receptor sequence
>8th5C (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
KPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHADAVYGQKEIHR
KVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFV
LAPEGSVANKFYVHNDIFRYQDEVF
3D structure
PDB8th5 Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication.
ChainC
Resolution2.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C N102 Q103 N89 Q90
BS02 peptide C P6 V11 F15 F33 E117 A121 N122 K123 F124 P2 V7 F11 F29 E104 A108 N109 K110 F111
BS03 peptide C R17 Q18 R13 Q14
External links
PDB RCSB:8th5, PDBe:8th5, PDBj:8th5
PDBsum8th5
PubMed38492217
UniProtQ13283|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)

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