Structure of PDB 8suv Chain C

Receptor sequence
>8suvC (length=128) Species: 9606 (Homo sapiens) [Search protein sequence]
SPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLK
MQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYS
LAKEQRLNFGDDIPSALRIAKKKRWNSI
3D structure
PDB8suv Interaction with the membrane-anchored protein CHIC2 constrains the ubiquitin ligase activity of CHIP
ChainC
Resolution1.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C K30 N34 F37 Y49 V61 N65 L68 K95 F98 Q102 F131 D134 K8 N12 F15 Y27 V39 N43 L46 K73 F76 Q80 F109 D112
External links
PDB RCSB:8suv, PDBe:8suv, PDBj:8suv
PDBsum8suv
PubMed
UniProtQ9UNE7|CHIP_HUMAN E3 ubiquitin-protein ligase CHIP (Gene Name=STUB1)

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