Structure of PDB 8spu Chain C

Receptor sequence
>8spuC (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
AKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAE
ILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNI
QAVLLPK
3D structure
PDB8spu Structural mechanism of LIN28B nucleosome targeting by OCT4.
ChainC
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C R29 R42 V43 G44 R77 R18 R31 V32 G33 R66
BS02 dna C K15 S16 R17 R20 R32 R77 K4 S5 R6 R9 R21 R66
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008150 biological_process
GO:0031507 heterochromatin formation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Cellular Component
External links
PDB RCSB:8spu, PDBe:8spu, PDBj:8spu
PDBsum8spu
PubMed37327775
UniProtQ16777|H2A2C_HUMAN Histone H2A type 2-C (Gene Name=H2AC20)

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