Structure of PDB 8slp Chain C

Receptor sequence
>8slpC (length=910) Species: 10116 (Rattus norvegicus) [Search protein sequence]
CKGEVNFKRSKFVKVPSNVAPSMLFELLLTEWHLPAPNLVVSLVGEERLF
AMKSWLRDVLRKGLVKAAQSTGAWILTSALHVGLARHVGQAVRDHSLAVR
VVAIGMASLDRILHRQLLDGTPIHYPADCPLDSNLSHFILVAELQLSLEK
HISQQRSSIQIPVLCLLVNGDPSTLERMSRAVEQAAPWLILGGIADVLAA
LVGQPHLLVPQVTEKQFREKFPSECFSWEAIVHWTELLQNIAAHPHLLTV
YDFEQEGSEDLDTVILKALVKACKSHSRDAQDYLDELKLAVAWDRVDIAK
SEIFNGDVEWKSCDLEEVMTDALVSNKPDFVRLFVDSGADMAEFLTYGRL
QQLYHSVSPKSLLFELLERKHEEGRLLPAFSLHEVSRVLKDFLHDACRGF
YQWLPDLSRKSEDPWRDLFLWAVLQNRYEMATYFWAMGREGVAAALAACK
IIKEMSHLEKEAEVARTMREAKYEQLALDLFSECYSNSEDRAFALLVRRN
HSWSRTTCLHLATEADAKAFFAHDGVQAFLTKIWWGDMATGTPILRLLGA
FTCPALIYTNLISFSEAAFLLTRWRKFWGAPVTVFLGNVVMYFAFLFLFS
YVLLVDFRPPPQGPSGSEVTLYFWVFTLVLEEIRQGFFTDTRLVKKFTLY
VEDNWNKCDMVAIFLFIVGVTCRMVPSVFEAGRTVLAIDFMVFTLRLIHI
FAIHKQLGPKIIIVERMMKDVFFFLFFLSVWLVAYGVTTQALLHPHDGRL
EWIFRRVLYRPYLQIFGQIPLDEIDEARVLYANWLVILLLVTFLLVTNVL
LMNLLIAMFSYTFQVVQGNADMFWKFQRYHLIVEYHGRPALAPPFILLSH
LSLVLKQVFRPDPVDQKIITWETVQKENFLSTMEKRRRDSEEEVLRKTAH
RVDLIAKYIG
3D structure
PDB8slp Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
ChainC
Resolution3.8 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA C Q225 D350 D353 Q160 D282 D285
BS02 CA C N807 D810 N656 D659
External links