Structure of PDB 8s8h Chain C

Receptor sequence

>8s8hC (length=220) Species: 284590 (Kluyveromyces lactis NRRL Y-1140) [Search protein sequence]

EEKGWVPVTKLGRLVKAGKISSIEEIFLHSLPVKEFQIIDQLLPNLKDEV
MNIKPVQKQTRAGQRTRFKAVVVVGDSNGHVGLGIKTAKEVAGAIRAGII
IAKLSVIPIRRGYWGTNLGQPHSLATKTSGKCGSVSVRLIPAPRGSGIVA
SPAVKKLMQLAGVEDVYTSSTGSTRTLENTLKAAFVAIGNTYGFLTPNLW
EVQALTPSPMDVYADYATAS

3D structure

PDB

8s8h Structural basis of AUC codon discrimination during translation initiation in yeast.

Chain

Resolution

4.0 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	C	K69 K89 V91 Q92 K93 Q94 T95 R96 Q99 K104 K121 S164 K166 C167 G168 S169 R173 V184 A185 Y202 T203 S205 T206 S208 T209 R210 T211 N214 K217	K34 K54 V56 Q57 K58 Q59 T60 R61 Q64 K69 K86 S129 K131 C132 G133 S134 R138 V149 A150 Y167 T168 S170 T171 S173 T174 R175 T176 N179 K182
BS02	rna	C	F103 V126	F68 V91

External links

PDB	RCSB:8s8h, PDBe:8s8h, PDBj:8s8h
PDBsum	8s8h
PubMed	39193907
UniProt	Q6CKL3

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