Structure of PDB 8rpl Chain C

Receptor sequence
>8rplC (length=627) Species: 2026724 (Chloroflexota bacterium) [Search protein sequence]
LIEERLFPPPEDIVKNANITAYMKSKGFDDYEAFYRWSLANRFEFWNDMA
KELHWFEPWKSTFEWTDKPFFKWFTDGKFNIAYNCLDRYMGTPIEDKVAF
YWEGDDGSSRAYTYKEMYVLTNRVAKVLQNQGVKKGDRVAIYMPMIPEMA
ASVLACARLGAPHMVVFGGFAASSLRDRMNDCDAKVLITADGGYRGGKVI
ELKKIADEAVAETPTIEKVFVQRHTGFEVPMAEGRDVYLDVLLNDIPEDT
VVPCEPVDSEDMLYILYTSGSTGKPKGVVHVHGGYAVGCYATTKFVFDIK
PSDVFWCTADIGWVTGHSYTIYGPMMNAASIVLFEGIPTYPAADRFWSIV
EKYKVNIIYTAPTAIRSLMRFGEELPARHDLSSLRILGTVGEPINPEAWM
WYRKNIGHNELPIMDTWWQTETGMILISPTPILPLKPGSASRPLPTIEAD
VVNKDGKPVGPEHGGFLIIRHPWPAQMRTIFGDPDRYKTYWETIPDVYFA
GDAATMDKMGYFRIQGRVDDVIKVSGHRLGSMEIESSLVSHPAVAEAAAI
GKPDEVKGEHVKVFVILRNGVEPTESLAVELKRHVRTLVGPLATPDELEF
VTSLPKTRSGKIMRRVVRARELGEPVG
3D structure
PDB8rpl Acetyl-CoA synthetase activity is enzymatically regulated by lysine acetylation using acetyl-CoA or acetyl-phosphate as donor molecule.
ChainC
Resolution2.37 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6R9 C G404 E405 P406 T429 W430 W431 Q432 T433 D515 R530 K536 R541 G391 E392 P393 T416 W417 W418 Q419 T420 D502 R517 K523 R528
BS02 MG C V552 H554 V557 V539 H541 V544
Gene Ontology
Molecular Function
GO:0003987 acetate-CoA ligase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
Biological Process
GO:0006085 acetyl-CoA biosynthetic process
GO:0019427 acetyl-CoA biosynthetic process from acetate
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8rpl, PDBe:8rpl, PDBj:8rpl
PDBsum8rpl
PubMed39019872
UniProtA0A535FEC2

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