Structure of PDB 8roa Chain C

Receptor sequence
>8roaC (length=364) Species: 9606 (Homo sapiens) [Search protein sequence]
GFLKLIEIENFKSYKGRQIIGPFQRFTAIIGPNGSGKSNLMDAISFVLGE
KTSNLRVKTLRDLIHGAPVGKPAANRAFVSMVYSEEGAEDRTFARVIVGG
SSEYKINNKVVQLHEYSEELEKLGILIKARNFLVFQGAVESIAMKNPKER
TALFEEISRSGELAQEYDKRKKEMVKAEEDTQFFEAARKRAKKAKQAFEQ
IKKERFDRFNACFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGI
NYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDQIDAA
LDNTNIGKVANYIKEQSTCNFQAIVISLKEEFYTKAESLIGVYPEQGDCV
ISKVLTFDLTKYPD
3D structure
PDB8roa The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.
ChainC
Resolution2.4355 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP C K13 G35 G37 K38 S39 N40 H66 G67 P69 C1210 V1211 K12 G34 G36 K37 S38 N39 H65 G66 P68 C349 V350
External links
PDB RCSB:8roa, PDBe:8roa, PDBj:8roa
PDBsum8roa
PubMed39240714
UniProtQ14683|SMC1A_HUMAN Structural maintenance of chromosomes protein 1A (Gene Name=SMC1A)

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