Structure of PDB 8qzx Chain C

Receptor sequence
>8qzxC (length=334) Species: 5722 (Trichomonas vaginalis) [Search protein sequence]
LVKGYVPDDNGKFDFDKMLEQMKYCGFQATNLGLAIDQINEMLHYDYEPE
KKLFGLGGGVEGVKYKPRACKIFLGITSNLISSGMRDYIRFLVKHALVDV
VVCTAGGIEEDFIKCLAPTHMGEFFHDGHDLRKRGLNRIGNLIVPNKNYC
LFEDWIMPILDKCLEEQNTQGTKWTPSKLIHRLGLEINNEDSVWYWAAKN
NIPVYSPALTDGSIGDMIYFHSYNNPGLVLDLVEDIRDMNNEPLWATKTG
CIILGGGVVKHHIMNANLYRNGADFVVYVNTAHDFDGSDSGARPDEAVSW
GAISLEAKPVKVYAEVTLVLPLLVAGSFSKFLAE
3D structure
PDB8qzx Structural characterization of the (deoxy)hypusination in Trichomonas vaginalis questions the bifunctionality of deoxyhypusine synthase.
ChainC
Resolution3.01 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NAD C S107 N108 A134 G135 D240 G285 N309 T310 E344 V345 S78 N79 A105 G106 D211 G256 N280 T281 E315 V316
BS02 NAD C H290 D318 S319 H261 D289 S290
Gene Ontology
Molecular Function
GO:0034038 deoxyhypusine synthase activity
Biological Process
GO:0008612 peptidyl-lysine modification to peptidyl-hypusine
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8qzx, PDBe:8qzx, PDBj:8qzx
PDBsum8qzx
PubMed38923395
UniProtF1AQF9

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