Structure of PDB 8pxv Chain C

Receptor sequence
>8pxvC (length=632) Species: 239935 (Akkermansia muciniphila) [Search protein sequence]
QIIPKPAEITLFTGSPARLTPDSLIITETQDKAFLDQAGQLQQMLSAGTG
LPLPLKPAGQASKKAACIVIKKDPALAARGEEAYSIQSSPSGIILSAADA
RGIFYAGQSLVQMMPSVFHDRTGDKSAVRWNISETPFRITDYPRFSWRAL
MIDEARHFFGEKTIKQIIDQMALLKMNILHWHLTDDTGWRIEIKKYPRLT
SIGSKRRESEIGTWNSGKSDGTPHEGFYTQEQIRDIVQYAARRNITIVPE
IEMPGHASAAAVAYPFLSLKTPGEVPTTFIVNTAFDPTSEKTYAFLSDVL
DEVTAIFPGRIIHIGGDEVRYDKQWKGVPEIEEFMKKNGMKSYADVQMHF
TNRMSGIIAQKGRRMMGWNEIYGAKLDTNAVIQFWKGNTSLAKNAIRDGH
DVINSLHTSTYLDYSYGSIPLQKAYGFEPVFPGLEKQYHSRVKGLGAQVW
TEWISTPERLHYQAFPRACAFAEVGWTPAGKKDFPDFKKRLKAYSERMDL
MGIKFARNVISQIDKSDFFNTPRIGTWTPATLTREEHSFDVTKLVKASGK
HTVTLLYDKGAHAIEIESVALYENSREVSRDAHAGRSGAHKENIQYILNA
PAPRQGATYTVKANFKGAGGRDSHGTVYFETP
3D structure
PDB8pxv Towards automated crystallographic structure refinement with phenix.refine.
ChainC
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.52: beta-N-acetylhexosaminidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL C R159 D428 W465 E467 R156 D413 W450 E452
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004563 beta-N-acetylhexosaminidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0030203 glycosaminoglycan metabolic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8pxv, PDBe:8pxv, PDBj:8pxv
PDBsum8pxv
PubMed38684911
UniProtB2UN02

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