Structure of PDB 8pta Chain C

Receptor sequence
>8ptaC (length=351) Species: 9606 (Homo sapiens) [Search protein sequence]
NNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKL
SRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIV
MELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNI
VVKSDCTLKILDFGLARTAGTSFMMVVTRYYRAPEVILGMGYKENVDIWS
VGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYV
ENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRI
SVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
M
3D structure
PDB8pta Tunable c-Jun N-terminal kinase (JNK) inhibitors that target a specific cysteine by a reversible covalent bond
ChainC
Resolution2.41 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CIF C I32 V40 A53 L110 M111 D112 A113 N114 C116 Q117 L168 E217 I25 V33 A46 L103 M104 D105 A106 N107 C109 Q110 L161 E207
External links
PDB RCSB:8pta, PDBe:8pta, PDBj:8pta
PDBsum8pta
PubMed
UniProtP45983|MK08_HUMAN Mitogen-activated protein kinase 8 (Gene Name=MAPK8)

[Back to BioLiP]