Structure of PDB 8pk6 Chain C

Receptor sequence
>8pk6C (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]
MKIFSESHKTVFVVDHCPYMAESCRQHSKSLWTCSVESSMEYCRIMYDIF
PFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALAAVGPPNPRADPECS
ILHGLVAAVETLCKITEYQHEARTLLMENAERVGNRGRIICITNAKSDSH
VRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDR
SKKELSPVLTSEVHSVRAGRHLATKLNILVQQHFD
3D structure
PDB8pk6 Basis of gene-specific transcription regulation by the Integrator complex.
ChainC
Resolution3.21 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C L103 K147 M154 C158 E161 H166 L102 K146 M153 C157 E160 H165
External links
PDB RCSB:8pk6, PDBe:8pk6, PDBj:8pk6
PDBsum8pk6
PubMed38906142
UniProtQ9NVM9|INT13_HUMAN Integrator complex subunit 13 (Gene Name=INTS13)

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