Structure of PDB 8phd Chain C

Receptor sequence
>8phdC (length=306) Species: 9606 (Homo sapiens) [Search protein sequence]
PRGSHMKKEHVLHCQFSAWYPFFRGVTIKSVILPLPQNVKDYLLDDGTLV
VSGRWSDDENTATLTAPEFPEFATKVQEAINSLGGSVFPKLNWSAPRDAY
WIAMNSSLKCKTLSDIFLLFKSSDFITRDFTQPFIHCTDDSPDPCIEYEL
VLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEIRRCIQ
DFFKKHIQYKFLDEDFVFDIYRDSRGKVWLIDFNPFGEVTDSLLFTWEEL
ISENNLNGDFSEVDAQEQDSPAFRCTNSEPYLSYRLPKDFAHKLIDFLKL
KRNQQE
3D structure
PDB8phd Binding of human Cdc123 to eIF2 gamma.
ChainC
Resolution2.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C F102 K104 R111 W169 C170 L172 E177 R179 R193 N248 F88 K90 R97 W155 C156 L158 E163 R165 R179 N234
BS02 MG C D246 N248 D232 N234
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0044183 protein folding chaperone
GO:0046872 metal ion binding
Biological Process
GO:0006457 protein folding
GO:1905143 eukaryotic translation initiation factor 2 complex assembly
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8phd, PDBe:8phd, PDBj:8phd
PDBsum8phd
PubMed37507029
UniProtO75794|CD123_HUMAN Translation initiation factor eIF2 assembly protein (Gene Name=CDC123)

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