Structure of PDB 8pds Chain C

Receptor sequence
>8pdsC (length=365) Species: 694067 (Human metapneumovirus CAN97-83) [Search protein sequence]
MSLQGIHLSDLSYKHAILKESQYTIKRDVGTTTAVTPSSLQQEITLLCGE
ILYAKHADYKYAAEIGIQYISTALGSERVQQILRNSGSEVQVVLTRTYSL
GKIKNNKGEDLQMLDIHGVEKSWVEEIDKEARKTMATLLKESSGNIPQNQ
RPSAPDTPIILLCVGALIFTKLASTIEVGLETTVRRANRVLSDALKRYPR
MDIPKIARSFYDLFEQKVYHRSLFIEYGKALGSSSTGSKAESLFVNIFMQ
AYGAGQTMLRWGVIARSSNNIMLGHVSVQAELKQVTEVYDLVREMGPESG
LLHLRQSPKAGLLSLANCPNFASVVLGNASGLGIIGMYRGRVPNTELFSA
AESYAKSLKESNKIN
3D structure
PDB8pds Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
ChainC
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna C K171 A173 S174 R185 R186 R189 V190 L243 N246 Q250 G255 T257 W261 S314 I334 M337 Y338 R339 K171 A173 S174 R185 R186 R189 V190 L243 N246 Q250 G255 T257 W261 S314 I334 M337 Y338 R339
BS02 peptide C Y53 I103 R132 K133 M135 R151 S153 Y53 I103 R132 K133 M135 R151 S153
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8pds, PDBe:8pds, PDBj:8pds
PDBsum8pds
PubMed37993464
UniProtQ6WBA1|NCAP_HMPVC Nucleoprotein (Gene Name=N)

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