Structure of PDB 8pdr Chain C

Receptor sequence

>8pdrC (length=351) Species: 694067 (Human metapneumovirus CAN97-83) [Search protein sequence]

DLSYKHAILKESQYTIKRDVGTTTAVTPSSLQQEITLLCGEILYAKHADY
KYAAEIGIQYISTALGSERVQQILRNSGSEVQVVLTRTYSLGKIKNNKGE
DLQMLDIHGVEKSWVEEIDKEARKTMATLLKESSGNIPQNQRPSAPDTPI
ILLCVGALIFTKLASTIEVGLETTVRRANRVLSDALKRYPRMDIPKIARS
FYDLFEQKVYHRSLFIEYGKALGSSSTGSKAESLFVNIFMQAYGAGQTML
RWGVIARSSNNIMLGHVSVQAELKQVTEVYDLVREMGPESGLLHLRQSPK
AGLLSLANCPNFASVVLGNASGLGIIGMYRGRVPNTELFSAAESYAKSLK
E

3D structure

PDB

8pdr Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.

Chain

Resolution

4.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	C	Y53 I103 R132 K133 M135 R151 S153	Y44 I94 R123 K124 M126 R142 S144
BS02	rna	C	K171 A173 S174 R185 R186 R189 G255 T257 W261 S314 I334 M337 Y338 R339	K162 A164 S165 R176 R177 R180 G246 T248 W252 S305 I325 M328 Y329 R330
BS03	rna	C	R186 V190 S242 L243 N246	R177 V181 S233 L234 N237

Gene Ontology

	Molecular Function
GO:0003723	RNA binding

	Cellular Component
GO:0019013	viral nucleocapsid
GO:0019029	helical viral capsid
GO:0030430	host cell cytoplasm
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Cellular Component

External links

PDB	RCSB:8pdr, PDBe:8pdr, PDBj:8pdr
PDBsum	8pdr
PubMed	37993464
UniProt	Q6WBA1\|NCAP_HMPVC Nucleoprotein (Gene Name=N)

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