Structure of PDB 8pc6 Chain C

Receptor sequence
>8pc6C (length=107) Species: 8355 (Xenopus laevis) [Search protein sequence]
AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAE
ILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNI
QSVLLPK
3D structure
PDB8pc6 Multivalency of nucleosome recognition by LEDGF.
ChainC
Resolution3.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C A12 K15 R17 R20 R32 R77 A1 K4 R6 R9 R21 R66
BS02 dna C R29 R42 V43 K75 T76 R77 R18 R31 V32 K64 T65 R66
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8pc6, PDBe:8pc6, PDBj:8pc6
PDBsum8pc6
PubMed37615563
UniProtP06897|H2A1_XENLA Histone H2A type 1

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