Structure of PDB 8p5k Chain C

Receptor sequence
>8p5kC (length=268) Species: 9606 (Homo sapiens) [Search protein sequence]
TETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQ
TLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAM
RTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPANPNSIRV
KIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIV
YQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPAATSAPLRQLLLALLQR
NHKDRMDFDEFFHHPFLD
3D structure
PDB8p5k Crystal structures of ULK1 in complex with KCGS compounds
ChainC
Resolution2.209 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HVH C I22 H24 V30 A44 M92 Y94 C95 G98 D102 L145 I15 H17 V23 A37 M85 Y87 C88 G91 D95 L138
BS02 MG C E191 Y198 D199 H263 E180 Y187 D188 H252
BS03 MG C H136 D165 F166 F168 H129 D154 F155 F157
External links
PDB RCSB:8p5k, PDBe:8p5k, PDBj:8p5k
PDBsum8p5k
PubMed
UniProtO75385|ULK1_HUMAN Serine/threonine-protein kinase ULK1 (Gene Name=ULK1)

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