Structure of PDB 8oza Chain C

Receptor sequence
>8ozaC (length=216) Species: 9606 (Homo sapiens) [Search protein sequence]
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSE
QNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY
NPKYSVANDAGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGI
YFEPDCSSEDMDHGVLVVGYGFESNNKYWLVKNSWGEEWGMGGYVKMAKD
RRNHCGIASAASYPTV
3D structure
PDB8oza Human cathepsin L in complex with covalently bound CA-074 methyl ester
ChainC
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.15: cathepsin L.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WRH C Q19 G23 C25 G67 G68 D162 H163 G164 W189 Q19 G23 C25 G67 G68 D162 H163 G164 W185
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8oza, PDBe:8oza, PDBj:8oza
PDBsum8oza
PubMed38630165
UniProtP07711|CATL1_HUMAN Procathepsin L (Gene Name=CTSL)

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