Structure of PDB 8ox1 Chain C

Receptor sequence
>8ox1C (length=110) Species: 9606 (Homo sapiens) [Search protein sequence]
ARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT
AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLP
NIQAVLLPKK
3D structure
PDB8ox1 Structural basis of telomeric nucleosome recognition by shelterin factor TRF1.
ChainC
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C R11 A12 A14 K15 R17 R32 R42 R77 R2 A3 A5 K6 R8 R23 R33 R68
BS02 dna C R29 R42 V43 G44 A45 T76 R77 R20 R33 V34 G35 A36 T67 R68
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008285 negative regulation of cell population proliferation
GO:0031507 heterochromatin formation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Cellular Component
External links
PDB RCSB:8ox1, PDBe:8ox1, PDBj:8ox1
PDBsum8ox1
PubMed37624885
UniProtQ93077|H2A1C_HUMAN Histone H2A type 1-C (Gene Name=H2AC6)

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