Structure of PDB 8ouz Chain C

Receptor sequence
>8ouzC (length=308) Species: 9606 (Homo sapiens) [Search protein sequence]
GVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKALV
ALRRVLLAQFSAFPVNGADLYEELKTSTAILSTGIGSLDKLLDAGLYTGE
VTEIVGGPGSGKTQVCLCMAANVAHGLQQNVLYVDSNGGLTASRLLQLLQ
AKTQDEEEQAEALRRIQVVHAFDIFQMLDVLQELRGTVAQQVTGSSGTVK
VVVVDSVTAVVSPLLGGQQREGLALMMQLARELKTLARDLGMAVVVTNHI
TRDRDSGRLKPALGRSWSFVPSTRILLDTISGGRRMACLAKSSRQPTGFQ
EMVDIGTW
3D structure
PDB8ouz Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor.
ChainC
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C G110 S111 G112 K113 T114 Q115 R145 I311 G109 S110 G111 K112 T113 Q114 R144 I305
BS02 ATP C F270 K297 R300 Q301 F269 K291 R294 Q295
Gene Ontology
Molecular Function
GO:0000400 four-way junction DNA binding
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016887 ATP hydrolysis activity
GO:0043015 gamma-tubulin binding
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0000722 telomere maintenance via recombination
GO:0000723 telomere maintenance
GO:0000724 double-strand break repair via homologous recombination
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006974 DNA damage response
GO:0007131 reciprocal meiotic recombination
GO:0036297 interstrand cross-link repair
GO:0042148 DNA strand invasion
GO:0051276 chromosome organization
GO:0051726 regulation of cell cycle
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005657 replication fork
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005856 cytoskeleton
GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ouz, PDBe:8ouz, PDBj:8ouz
PDBsum8ouz
PubMed37344587
UniProtO75771|RA51D_HUMAN DNA repair protein RAD51 homolog 4 (Gene Name=RAD51D)

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