Structure of PDB 8omz Chain C

Receptor sequence
>8omzC (length=409) Species: 83334 (Escherichia coli O157:H7) [Search protein sequence]
RAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPATVLLFNGIG
TLLYLFICKGKIPAYLGSSFAFISPVLLLLPLGYEVALGGFIMCGVLFCL
VSFIVKKAGTGWLDVLFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQT
PDSKTIIISITTLAVTVLGSVLFRGFLAIIPILIGVLVGYALSFAMGIVD
TTPIINAHWFALPTLYTPRFEWFAILTILPAALVVIAEHVGHLVVTANIV
KKDLLRDPGLHRSMFANGLSTVISGFFGSTPNTTYGENIGVMAITRVYST
WVIGGAAIFAILLSCVPKLAAAIQMIPLPVMGGVSLLLYGVIGASGIRVL
IESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGMALATIVGIGLS
LIFKLISVL
3D structure
PDB8omz Interdomain-linkers control conformational transitions in an SLC23 elevator transporter
ChainC
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DMU C S370 I374 V377 S378 S367 I371 V374 S375
BS02 DMU C L353 I354 K357 Y360 L350 I351 K354 Y357
Gene Ontology
Molecular Function
GO:0015205 nucleobase transmembrane transporter activity
GO:0015210 uracil transmembrane transporter activity
GO:0015293 symporter activity
GO:0015505 uracil:monoatomic cation symporter activity
GO:0022857 transmembrane transporter activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0015857 uracil transport
GO:0055085 transmembrane transport
GO:0098721 uracil import across plasma membrane
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:8omz, PDBe:8omz, PDBj:8omz
PDBsum8omz
PubMed39209842
UniProtP0AGM7|URAA_ECOLI Uracil permease (Gene Name=uraA)

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