Structure of PDB 8ol1 Chain C

Receptor sequence
>8ol1C (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
ARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT
AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLP
NIQAVLLP
3D structure
PDB8ol1 Nuclear degradation of cGAS is essential for immune homeostasis
ChainC
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna C R11 A12 A14 K15 T16 R17 R20 R32 R42 R77 R2 A3 A5 K6 T7 R8 R11 R23 R33 R68
BS02 dna C R11 R29 R35 R42 V43 G44 K75 T76 R77 R2 R20 R26 R33 V34 G35 K66 T67 R68
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8ol1, PDBe:8ol1, PDBj:8ol1
PDBsum8ol1
PubMed38418882
UniProtQ96KK5|H2A1H_HUMAN Histone H2A type 1-H (Gene Name=H2AC12)

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