Structure of PDB 8ofi Chain C

Receptor sequence
>8ofiC (length=415) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]
MLQPGVNKFSLRMFGSQKAVEREQERVKSHPYSDFRFYWDLTMLLLMVGN
LIIIPVGITFFKPWIVFNVVSDTFFLIDLVLNSWFVVDFVSSIPVDYIFL
IVELRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVN
LIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSLNNMVNNSWGKQYSYALF
KAMSHMLCIGYGRQAPMGMSDVWLTMLSMIVGATCYAMFIGHATALIQSL
DSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESIL
GELSEPLREEIINFNCRKLVASMDPNFVTSMLTKLRFEVFQPGDYIIGKK
MYFIQHGVVSVLTKGNKETKLADGSYFGEICSVRADTYCRLYSLSVDNFN
EVLEEYPMMRRAFET
3D structure
PDB8ofi Structural determinants of ivabradine block of the open pore of HCN4.
ChainC
Resolution3.6 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VNZ C C479 Y507 I511 C208 Y236 I240
External links