Structure of PDB 8ki3 Chain C

Receptor sequence
>8ki3C (length=487) Species: 9606 (Homo sapiens) [Search protein sequence]
EMSSILEERILGADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFS
SGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGEELLGR
VVDALGNAIDGKGPIGSKTRRRVGLKAPGIIPRISVREPMQTGIKAVDSL
VPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGSDEKKKLYCIYVAI
GQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEY
FRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLL
ERAAKMNDAFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETEL
FYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVALLSRG
VRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFENAFLSH
VVSQHQALLGTIRADGKISEQSDAKLKEIVTNFLAGF
3D structure
PDB8ki3 Structure of Mycobacterium tuberculosis ATP synthase
ChainC
Resolution2.89 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C Q172 G174 K175 T176 S177 F357 Q432 Q166 G168 K169 T170 S171 F351 Q411
Gene Ontology
Molecular Function
GO:0002020 protease binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0032559 adenyl ribonucleotide binding
GO:0042288 MHC class I protein binding
GO:0043531 ADP binding
GO:0043532 angiostatin binding
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
Biological Process
GO:0001937 negative regulation of endothelial cell proliferation
GO:0006629 lipid metabolic process
GO:0006754 ATP biosynthetic process
GO:0014850 response to muscle activity
GO:0015986 proton motive force-driven ATP synthesis
GO:0042776 proton motive force-driven mitochondrial ATP synthesis
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0045471 response to ethanol
GO:0046034 ATP metabolic process
GO:0071549 cellular response to dexamethasone stimulus
GO:0071732 cellular response to nitric oxide
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005886 plasma membrane
GO:0008180 COP9 signalosome
GO:0009986 cell surface
GO:0016020 membrane
GO:0016469 proton-transporting two-sector ATPase complex
GO:0031090 organelle membrane
GO:0045121 membrane raft
GO:0045259 proton-transporting ATP synthase complex
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)
GO:0045267 proton-transporting ATP synthase, catalytic core
GO:0070062 extracellular exosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ki3, PDBe:8ki3, PDBj:8ki3
PDBsum8ki3
PubMed38961288
UniProtP25705|ATPA_HUMAN ATP synthase subunit alpha, mitochondrial (Gene Name=ATP5F1A)

[Back to BioLiP]