Structure of PDB 8k1o Chain C

Receptor sequence
>8k1oC (length=212) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
VPIEIRGLTKHFGSVRALDGLDLTVREGEVHGFLGPNGAGKSTTLRILLG
LVKADGGSVRLLGGDPWTDAVDLHRHIAYVPGDVTLWPSLTGGETIDLLA
RMRGGIDNARRAELIERFGLDPTKKARTYSKGNRQKVSLISALSSHATLL
LLDEPSSGLDPLMENVFQQCIGEARQRGVTVLLSSHILAETEALCEKVTI
IRAGKTVESGSL
3D structure
PDB8k1o mycobacterial efflux pump, AMPPNP bound state
ChainC
Resolution2.9 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP C T135 S137 T128 S130
BS02 ANP C F19 N44 G47 K48 S49 T50 H193 F12 N37 G40 K41 S42 T43 H186
Gene Ontology
Biological Process
GO:0046677 response to antibiotic
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8k1o, PDBe:8k1o, PDBj:8k1o
PDBsum8k1o
PubMed
UniProtO86311|MEATP_MYCTU Multidrug efflux system ATP-binding protein Rv1218c (Gene Name=Rv1218c)

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