Structure of PDB 8k1n Chain C

Receptor sequence
>8k1nC (length=530) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
RGSGFTGTLGLLRLYLRRDRVSLPLWVLLLSVPLATVYIASVETVYPDRS
ARAAAAAAIMASPAQRALYGPVYNDSLGAVGIWKAGMFHTLIAVAVILTV
IRHTRADEESGRAELIDSTVVGRYANLTGALLLSFGASIATGAIGALGLL
ATDVAPAGSVAFGVALAASGMVFTAVAAVAAQLSPSARFTRAVAFAVLGT
AFALRAIGDAGSGTLSWCSPLGWSLQVRPYAGERWWVLLLSLATAAVLTV
LAYRLRAGRDVGAGLIAERPGAGTAGPMLSEPFGLAWRLNRGSLLLWTVG
LCLYGLVMGSVVHGIGDQLGDNTAVRDIVTRMGGTGALEQAFLALAFTMI
GMVAAAFAVSLTLRLHQEETGLRAETLLAGAVSRTHWLASHLAMALAGSA
VATLISGVAAGLAYGMTVGDVGGKLPTVVGTAAVQLPAVWLLSAVTVGLF
GLAPRFTPVAWGVLVGFIALYLLGSLAGFPQMLLNLEPFAHIPRVGGGDF
TAVPLLWLLAIDAALITLGAMAFRRRDVRC
3D structure
PDB8k1n mycobacterial efflux pump, substrate-bound state
ChainC
Resolution3.0 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RFP C Y56 S59 K102 I346 F360 M367 Y38 S41 K84 I328 F342 M349
Gene Ontology
Biological Process
GO:0046677 response to antibiotic
Cellular Component
GO:0005886 plasma membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:8k1n, PDBe:8k1n, PDBj:8k1n
PDBsum8k1n
PubMed
UniProtO05318|MEPRM_MYCTU Multidrug efflux system permease protein Rv1217c (Gene Name=Rv1217c)

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