Structure of PDB 8jv7 Chain C

Receptor sequence
>8jv7C (length=320) Species: 9646 (Ailuropoda melanoleuca) [Search protein sequence]
WIFHALVFSYISFALISDKRYQKKEPLISSVHTKVKGIAEVKAEILENGM
KKMVSGVFDTADYTFPLQGNSFFVMTNFIKTEGQQQGLCPDFPTARTICS
SDRGCKKGRMDPQSKGIQTGRCVVYKERLKTCEVSAWCPIEEVKDAPRPA
LLNSAENFTVLIKNNIDFPGHNYTTRNILPGVNITCTFHKTQNPQCPIFR
LGDIFQETGDSFSDVAIQGGIMGIEIYWDCNLDGWFHHCRPKYSFRRLDD
KTTSESLYPGYNFRYAKYYKENNVEKRTLIKVFGIRFDILVFGTGGKFNV
IQLAVYIGSVISYFGLATVF
3D structure
PDB8jv7 Structural insights into the orthosteric inhibition of P2X receptors by non-ATP-analog antagonists
ChainC
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UO6 C Q143 Y288 R294 K311 Q113 Y258 R264 K281
Gene Ontology
Molecular Function
GO:0001614 purinergic nucleotide receptor activity
GO:0004931 extracellularly ATP-gated monoatomic cation channel activity
GO:0005216 monoatomic ion channel activity
GO:0005524 ATP binding
Biological Process
GO:0006811 monoatomic ion transport
GO:0033198 response to ATP
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8jv7, PDBe:8jv7, PDBj:8jv7
PDBsum8jv7
PubMed38578670
UniProtG1M6C4

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