Structure of PDB 8juw Chain C

Receptor sequence
>8juwC (length=528) Species: 9606 (Homo sapiens) [Search protein sequence]
SSVRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPG
TGKTLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQA
YQMRPSIIFFDQIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDSRGEIVV
IGATNRLDSIDPALRRPGRFDREFLFSLPDKEARKEILKIHTRDWNPKPL
DTFLEELAENCVGYCGADIKSICAEAALCALRRRYPQIYTTSEKLQLDLS
SINISAKDFEVAMQKMIPASQRAVTSPGQALSTVVKPLLQNTVDKILEAL
QRVFPHAYQPMSFRPRILIVGEPGFGQGSHLAPAVIHALEKFTVYTLDIP
VLFGVSTTSPEETCAQVIREAKRTAPSIVYVPHIHVWWEIVGPTLKATFT
TLLQNIPSFAPVLLLATSDKPHSALPEEVQELFIRDYGEIFNVQLPDKEE
RTKFFEDLILKQAAKPPHERLKNLLKTVVKKSQNYNIFQLENLYAVISQC
IYRHRKDHDKTSLIQKMEQEVENFSCSR
3D structure
PDB8juw Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
ChainC
Resolution3.79 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C P469 G472 K473 T474 I607 H611 P49 G52 K53 T54 I187 H191
BS02 ATP C R586 R589 R166 R169
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:8juw, PDBe:8juw, PDBj:8juw
PDBsum8juw
PubMed37770645
UniProtQ6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (Gene Name=ATAD2)

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