Structure of PDB 8jr0 Chain C

Receptor sequence
>8jr0C (length=530) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
TIPADDIQSAIEEYVSSFEEVGTVVDAGDGIAHVEGLPSVMTQELLEFPG
GILGVALNLDEHSVGAVILGDFENIEEGQQVKRTGEVLSVPVGDGFLGRV
VNPLGQPIDGRGDVDSDTRRALELQAPSVVHRQGVKEPLQTGIKAIDAMT
PIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWESGDPKKQVRCVYVAIG
QKGTTIAAVRRTLEEGGAMDYTTIVAAAASESAGFKWLAPYTGSAIAQHW
MYEGKHVLIIFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLE
RCAKLSDDLGGGSLTGLPIIETKANDISAYIPTNVISITDGQCFLETDLF
NQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYRELEAFAAFA
SDLDAASKAQLERGARLVELLKQPQSQPMPVEEQVVSIFLGTGGHLDSVP
VEDVRRFETELLDHMRASEEEILTEIRDSQKLTEEAADKLTEVIKNFKKG
FAAVVPDEHVEALDEDKLAKEAVKVKKPAP
3D structure
PDB8jr0 Structure of Mycobacterium tuberculosis ATP synthase
ChainC
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.2.2: H(+)-transporting two-sector ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C R174 K175 G177 K178 T179 A180 R365 Q435 R164 K165 G167 K168 T169 A170 R355 Q425
BS02 ADP C V374 S375 R376 V364 S365 R366
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0032559 adenyl ribonucleotide binding
GO:0043531 ADP binding
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:0046034 ATP metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall
GO:0045259 proton-transporting ATP synthase complex
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8jr0, PDBe:8jr0, PDBj:8jr0
PDBsum8jr0
PubMed38961288
UniProtP9WPU7|ATPA_MYCTU ATP synthase subunit alpha (Gene Name=atpA)

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