Structure of PDB 8jon Chain C

Receptor sequence

>8jonC (length=485) Species: 1140 (Synechococcus elongatus PCC 7942 = FACHB-805) [Search protein sequence]

LSEVQKMPTMIEGFDDISHGGLPTGRSTLVSGTSGTGKTLFSIQFLYNGI
TEFDEPGIFVTFEESPQDIIKNARSFGWNLQKLVDQGKLFILDASPDPDG
QEVAGGFDLSALIERINYAIQKYKARRVSIDSVTAVFQQYDAASVVRREI
FRLVARLKQIGVTTVMTTERIDEYGPIARYGVEEFVSDNVVILRNVLEGE
RRRRTVEILKLRGTTHMKGEYPFTINDHGINIFPLGAMRLTQRSSNVRVS
SGVPRLDEMCGGGFFKDSIILATGATGTGKTLLVSKFIENACQNKERAIL
FAYEESRAQLLRNASSWGIDFEEMERQGLLKIICAYPESAGLEDHLQIIK
SEIGDFKPSRIAIDSLSALARGVSNNAFRQFVIGVTGYAKQEEITGFFTN
TSDQFMGSHSITDSHISTITDTILLLQYVEIRGEMSRAINVFKMRGSWHD
KGIREYVITDKGPEIKDSFRNFERIISGSPTRITV

3D structure

PDB

8jon Adaptation of ancient cyanobacterial clock to the day length ~ 0.95 Ga ago

Chain

Resolution

2.51 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.7.11.1: non-specific serine/threonine protein kinase.
3.6.4.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	ATP	C	K228 R230 T233 H234	K210 R212 T215 H216
BS02	ADP	C	M462 S465 H467	M444 S447 H449
BS03	ATP	C	G53 T54 G55 K56 T57 L58 S93 F94 I243 N244	G35 T36 G37 K38 T39 L40 S75 F76 I225 N226
BS04	MG	C	T57 D149	T39 D131
BS05	ADP	C	G295 G297 K298 T299 L300 W335 R455 I476 T477 D478	G277 G279 K280 T281 L282 W317 R437 I458 T459 D460

Gene Ontology

	Molecular Function
GO:0000287	magnesium ion binding
GO:0004674	protein serine/threonine kinase activity
GO:0004712	protein serine/threonine/tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016787	hydrolase activity
GO:0016887	ATP hydrolysis activity
GO:0042802	identical protein binding
GO:0044024	histone H2AS1 kinase activity
GO:0046872	metal ion binding
GO:0106310	protein serine kinase activity

	Biological Process
GO:0006338	chromatin remodeling
GO:0007623	circadian rhythm
GO:0009649	entrainment of circadian clock
GO:0016310	phosphorylation
GO:0042754	negative regulation of circadian rhythm
GO:0048511	rhythmic process
GO:0070297	regulation of phosphorelay signal transduction system

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:8jon, PDBe:8jon, PDBj:8jon
PDBsum	8jon
PubMed
UniProt	Q79PF4\|KAIC_SYNE7 Circadian clock oscillator protein KaiC (Gene Name=kaiC)

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