Structure of PDB 8jnr Chain C

Receptor sequence
>8jnrC (length=184) Species: 9606 (Homo sapiens) [Search protein sequence]
MRVIDREGVYEISLSPTGVSRVCLYPGFVDVKEADWILEQLSQDVPWKQR
TDITYQQPRLTAWYEPNPHWHPVLRTLKNRIEENTGHTFNSLLCNLYRNE
KDSVCWHSDDEPSLGRSPIIASLSFGATRTFEMRKKPPRVKIPLDHGTLL
IMEGATQADWQHRVPKEYHSREPRVNLTFRTVYP
3D structure
PDB8jnr The Molecular Basis of Human ALKBH3 Mediated RNA N1-methyladenosine (m1A) Demethylation
ChainC
Resolution3.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
1.14.11.54: mRNA N(1)-methyladenine demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN C H191 D193 H257 H107 D109 H162
Gene Ontology
Molecular Function
GO:0051213 dioxygenase activity
Biological Process
GO:0006281 DNA repair
GO:0006307 DNA alkylation repair

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Molecular Function
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Biological Process
External links
PDB RCSB:8jnr, PDBe:8jnr, PDBj:8jnr
PDBsum8jnr
PubMed38158383
UniProtQ96Q83|ALKB3_HUMAN Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (Gene Name=ALKBH3)

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