Structure of PDB 8jkn Chain C

Receptor sequence
>8jknC (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
NGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDYNREEDAAL
FKAWALFKGKFREGIDKPDPPTWKRRLRCALNKSNDFEELVERSQLDISD
PYKVYRIVP
3D structure
PDB8jkn Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
ChainC
Resolution2.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C W54 H56 A57 P91 K94 R98 W34 H36 A37 P71 K74 R78
BS02 dna C G22 L24 W74 K78 K80 R96 C99 K103 G2 L4 W54 K58 K60 R76 C79 K83
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8jkn, PDBe:8jkn, PDBj:8jkn
PDBsum8jkn
PubMed37683642
UniProtF2Z3D5

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