Structure of PDB 8j28 Chain C

Receptor sequence
>8j28C (length=267) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
SRAFAKDVKRIVVKVGTAVVTGKGGRLALGRLGAICEQLAELNSDGFEVI
LVSSGAVGLGRQRLRYRQLVNSSFADLQKPQMELDGKACAGVGQSSLMAY
YETMFDQLDVTVAQMLVTDSSFRDKDFRKQLSETVKAMLRMRVIPVFNEN
DAISTTGIFWDNDSLAALLSLELKADLLILLSDVEGLYTGPPSDSTSKLI
HTFIKEKHQDEITFGRGGMTAKVKAAVNAAYGGVPVIITSGYAAENISKV
LRGLRVGTLFHQDAHLW
3D structure
PDB8j28 GK monomer complexes with G5P and ADP
ChainC
Resolution3.7 Å
3D
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Enzymatic activity
Enzyme Commision number 1.2.1.41: glutamate-5-semialdehyde dehydrogenase.
2.7.2.11: glutamate 5-kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C V76 N77 S78 S79 A81 V70 N71 S72 S73 A75
BS02 peptide C Y72 F80 Y66 F74
BS03 peptide C Y72 L75 V76 F80 L83 Q84 Y66 L69 V70 F74 L77 Q78
BS04 ADP C S196 V198 Y202 G204 T227 G229 M239 S182 V184 Y188 G190 T213 G215 M219
BS05 RGP C S60 R236 G237 S54 R216 G217
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004349 glutamate 5-kinase activity
GO:0004350 glutamate-5-semialdehyde dehydrogenase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Biological Process
GO:0006561 proline biosynthetic process
GO:0009084 glutamine family amino acid biosynthetic process
GO:0009555 pollen development
GO:0009793 embryo development ending in seed dormancy
GO:0016310 phosphorylation
GO:0055129 L-proline biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0009506 plasmodesma
GO:0009507 chloroplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8j28, PDBe:8j28, PDBj:8j28
PDBsum8j28
PubMed
UniProtP54888|P5CS2_ARATH Delta-1-pyrroline-5-carboxylate synthase B (Gene Name=P5CSB)

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